A new study presented at the Congress of the EHRA 2025 of the European Cardiology Society shows that the connection between the use of antidepressants (AD) and the increased risk of sudden death (SC), especially for those with long -term drugs.

Sudden heart death, defined as an unexpected mortality due to a heart-related problem, usually occurs within an hour after the onset of symptoms or within 24 hours in cases that are not amenable. Also Read Your antidepressants make you gain weight? The shocking new study reveals the truth
For people who have not reached 39 years, the main reasons often thickening the heart muscle or electrical heart problems, while in the elderly it is likely to be bound by narrowed blood vessels.
Previous studies have shown that people with mental disorders face more risks of both general mortality and sudden death. However, the specific influence of antidepressants on the risk of SCD remains unclear.
Recent studies conducted by scientists in Denmark have studied death among residents between the ages of 18 and 90 in 2010, examining the death and exposing report.
The study found that people who are treated with antidepressants had a much higher frequency of sudden heart death compared to those who do not use such medicines.
Conclusions of the study:
The cohort of 643 999 individuals, which were prescribed by antidepressants, was compared to the total population, which had 4.3 million residents.
Among those who were exposed to antidepressants, 1,981 cases of sudden heart death were recorded compared to 4.021 in an uninformed group. Also Read Can conventional antidepressants be key to combat fatal infections? The study shows new conclusions
The SCD risk was higher in all age groups for those who were on antidepressants, with marked differences depending on the duration of exposure.
When the data was adjusted for age, gender and comorbidities, people who used antidepressants for 1 – 5 years had 56 percent higher risk of sudden death than the overall population.
Those who have used medicines for six or more years have faced a 2.2 -fold risk.
The study also found that young people had more significantly affected the longer use of antidepressants.
For those at the age of 30-39, the risk of sudden death was almost three times higher, and 1 to 5 years of exposure to those who have been using antidepressants for six or more years.
In the elderly, especially those at the age of 50-59, the risk of sudden heart death doubled from 1 to 5 years of using antidepressants and increased four times with six or more years. Also Read “I tried everything”: the mental struggle resistant to the treatment of depression and what needs to be changed
However, the risk increased in people over 70 years, with less significant difference between smaller and longer exposure periods.
Dr. Jasmin Mujanovich, co-author of the study with RigSpitalet Hjertcentret in Copenhagen, explained: to the antidepressants in the general population. “
D -r Mujanovich also suggested that the increased risk may be the result of potential adverse effects of antidepressants, but added, “during the effects of antidepressants can also serve a marker for more serious basic diseases. Both poor health, poor health, and poor health. “
This new study emphasizes the need for further research to better understand the potential cardiovascular risks associated with antidepressants, especially for prolonged use.
As the study emphasizes, people who use this medicine for long periods may encounter much greater risk of sudden death, emphasizing the importance of careful monitoring and managing their health.