Alkaptonuria: Why is it getting black urine? The urologist explains the long -term consequences

Alkaptonuria-ravant genetic disorder caused by the deficiency of the homagentate 1.2-diaxygenase enzyme. In an interview with ht lifestyle, dr obhishek agrawal, consultant Uralogist, Jupiter Hospital thaneed Why turns Urine Black, “This enzyme is essential for breaking download download, a BYPRODUCTUCT ACID METABOLISM The Enzyme is Deficient, Homogentisic Accumulates in the Body and is Exposure to Axure. Also Read World kidney day 2025: What can your urine reveal about kidney health? Doctor explains

Early signs of Alkaptonuria:

“Black change in urine color is often the earliest and most noticeable sign of the disease, usually in infancy or early childhood. However, many people with alkalonuria do not experience other symptoms to the next life. The extension of homogentic acid for decades leads to a state called ahronosis, where I get it in agrarian damage “, which is caused to the agrarian damage” agro “, which is the agrarian damage” agro “, which is caused by the agro, which is agro.” explained.

Long -term exposure to alkaptonuria:

• Joint disease: One of the most significant long -term effects of alkaptonuria is a degenerative joint disease. The deposition of homogentisic acid in the cartilage causes the joints to become fragile and prone to wear. Often, patients develop severe arthritis, especially in the spine, hips and knees, 30s or 40s. This joint damage can lead to chronic pain, reduced mobility and decreased quality of life. Also Read Blood in the urine: If you worry and what diagnostic steps should be taken
• Stones of the kidneys and prostate: The accumulation of homogentic acid can crystallize in the kidneys and prostate, leading to stone formation.
• Pigmentation: Patients can also experience dark pigmentation in the ears, skin and sclera (white part of the eyes), which is a noticeable sign of the progression of the disease.

Diagnosis and treatment Alkaptonuria:

“Although there is now no medicine for alkalonuria, early diagnosis and symptoms can improve patients’ results. Treatment is usually focused on relieving pain, maintaining joint function and monitoring cardiovascular and renal complications,” the urologist explained. Also Read UTI about lift among men: Doctor blaming lifestyles and stress for this disturbing trend

Note for readers: This article is intended only for information purposes rather than to replace professional medical advice. Always seek the advice of a doctor with any medical issues.