Can painkillers lead to kidney disease? Doctor explains risk factors, prevention tips


March 14, 2025. 16:45

Looking drugs, especially from the NSAID family, are known for causing kidney disease when used in excess. Know the prevention tips to remain safe.

Failure drugs are prescribed by a doctor, especially for the treatment of pain and inflammation. However, there is a certain group of drugs called NSAIDs, which are considered dangerous to kidney health when used in excess. In an interview with HT Lifestyle, D -R -Harsh, the nephrologist’s consultant and transplant doctor, the general hospital Amin Amen, Water, Gujarat explained the danger of excessive consumption. Also Read World Kidney Day 2025: Does stress bring to your kidneys? 7 Simple ways to manage it to improve kidney health

Excess PF consumption painkillers can have a serious impact on kidney health (Shuttestock)
Excess PF consumption painkillers can have a serious impact on kidney health (Shuttestock)

“Nonsteroidal anti -inflammatory drugs (NSAIDs), such as diclofenac, ibuprofen, Aceclofen and Piroxics, are usually intended for the treatment of pain and inflammation. Chronic or excessive intake of these drugs has a deep effect on the function of the kidneys, which leads to acute kidney injury. It is shown that up to 50% of patients consuming NSAIDs can adversely affect renal functions, especially those who have previous risk factors, “-Dadov the nephrologist.

Risk factors for kidney disease

The doctor further explained that certain risk factors could contribute to kidney disease among people who consume NSAIDs:

  • Chronic kidney disease (HBP) or preliminary kidney damage history, as preliminary conditions put the kidneys at a greater risk of further damage.
  • Dehydration because dehydration increases the load on the kidneys and makes them vulnerable to NSAID damage.
  • Heart, liver or kidney disease, as these conditions affect kidney function and increase the risk of kidney damage during NSAIDs.
  • Simultaneous administration of radios, such as agents used in CT, reduces kidney function when provided with NSAIDs.
  • Other nephrotoxic drugs, such as certain antibiotics when administered with NSAIDs.
  • Increased age after the functionality of the kidneys is reduced with increasing age.
  • Hypercalcemia (raised calcium) also increases the risk of kidney damage.
  • Long -term use of NSAIDs can potentially cause cumulative nephrotoxicity.
Know the ways to stay safe from the effects of painkillers on the kidneys (Shuttestock)
Know the ways to stay safe from the effects of painkillers on the kidneys (Shuttestock)

How can painkillers cause kidney disease?

“NSAIDs are harmful to the kidneys as a result of induction of lawless and non -independent ways of hemodynamic disorders, changing blood flow, eventually leading to Aki. Long nitrization of residues of protein peroxinitritis causes chronic nephritis (inflammation of the interstate and tube in the kidneys Visiting waste filtering, ” – explained the D -Rus Kharhe. Also Read World kidney Day 2025: Doctor shares the symptoms of chronic kidney disease, which should be monitored, risk factors, prevention tips

Preventive measures to maintain good kidney health

  • It is necessary to use the minimum effective dose of NSAIDs for the shortest possible time to help manage the main cause of pain.
  • Identification of the cause, origin and long time pain helps in choosing appropriate pain management.
  • In addition to NSAIDs, unauthorized herbal drugs and vitamin D supplements are harmful to the kidneys when abuse or excess. Also Read World Kidney Day 2025: 5 Best Life Changes to reduce the risk of kidney disease by 50%

Note for readers: This article is intended only for information purposes rather than to replace professional medical advice. Always seek the advice of a doctor with any medical issues.

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