Perhaps you may show braking to adapt to changes or grow but your brain is not. In fact, an adult human brain continues to grow new neurons, even when they age. Yes, that’s right. A new study revealed convincing evidence that neurons at the center of the brain, hippocampus, continue to form at the late age.The study, headed by the Carolinsky Institute Researchers in Sweden, has found answers to a long -debated and fundamental question of brain adaptation. The results of the study were published in the journal Science. Neurons continue to form into late adulthood
Hippocampus is a region in the brain responsible for tuition and memory. It also is responsible for emotional regulation. In 2013, a group of researchers of the Karolinskaya Institute showed that new neurons could be formed in the hippocampus of adults. In order to confirm this, they measured carbon-14 levels into DNA from brain tissue. However, it was still discussed because of the lack of obvious evidence that the cells preceded by the new neurons, known as neuronne cells, actually exist and divide into adults.“Now we have managed to determine these cells of origin, which confirms that the hippocampus in the hippocampus has a constant formation of neurons,” said Jonas Friesen, a professor of stem cell research at the Department of Cells and Molecular Biology, the Caroling Institute that directed research. Exploration
The new study, however, appealed to the help of advanced brain tissue methods from people between the ages of 0 and 78 from several international biobans. Using the RNA Nucleus sequence, they studied the properties of the cell. They combined it with machine training and identified different stages of neuronal development. They also used Rnascope and Xenium to further understand the process. What they found was strange. These methods have confirmed that the recently formed cells were located in a certain area of the hippocampus called a toothbrush. This area is important for the formation of memory, learning and cognitive flexibility.How is this study significant?
The results of this study are the hope of new therapies. The results suggest that adult neurons are similar to mice, pigs and monkeys. However, there are some differences in which the genes are active. There were also great variations between people – some adults had many cells of neurons, others are unlikely at all.“It gives us an important part of the puzzle in understanding how the human brain works and changes throughout life. Our study can also have consequences for the development of regenerative therapies that stimulate neurogenesis in neurodegenerative and psychiatric disorders,” said Jonas Frysen.
