There are more than a hundred hormones in the human body. By sending information to its organs, skin, muscles and other tissues with blood, hormones help your body coordinate different processes.
Most tissues (mainly glands) that produce and secrete hormones are part of your endocrine system. In an interview with HT Lifestyle, Dr. Varini H, Senior Consultant – Obestertrics and Gynecologist Milan’s Birth Center in Bengalur, “Many body functions such as metabolism, homeostasis (continuous internal balance), which includes blood pressure and sugar regulation, fluid (water) and the balance of electrolytes, body temperature, growth and development, sexual function, reproduction, sleep cycle and mood, all regulated by hormones. “
Further she found: “A small amount of hormones can have a great influence. From this, even small variations can have a great effect on your body and cause medical care. On the other hand, hormonal imbalance or expanding impact on certain hormones They can cause reproductive malignancies, such as progesterone and estrogen, the risk of ovarian, endometrial and breast, among other reproductive cancers. .
Factors that cause the likelihood of reproductive cancer –
1. Reproductive samples: The risk of breast cancer can be increased by early menstruation, late menopause and never give birth.
2. The use of treatment with hormonal replacement (HRT), especially if estrogen and gestagen are combined, can increase the risk of breast cancer.
3. Obesity: The risk of endometrial cancer as well as breast cancer can grow with heavy weight.
4. Endometriosis: Ovarian ovarian cancer is closely linked to endometriosis.
The influence of hormones on reproductive rivers
The health of the reproductive system depends on hormones such as testosterone, progesterone and estrogen. However, several malignancies were associated with the chronic or excessive impact of these hormones:
1. Breast cancer: Progesterone and estrogen play an important role in the development of breast cancer. The risk is increased for women who use hormone replacement therapy (ZGT) over a long period of time, have early menarche or have late menopause. Breast cancer cells that are sensitive to hormones can grow more quickly as a result of these hormones.
2. Ovarian cancer: Studies show that the likelihood of a woman’s ovarian cancer can be affected by hormonal factors, such as the number of ovulation cycles she is experiencing. Disorders that interfere with the natural balance of hormones such as polycystic ovaries (PCOs) may also participate.
3. Cancer endometrium: One of the main risk factors of endometrial cancer is an unacceptable effect of estrogen, which occurs when progesterone levels are not high enough to balance estrogen. Because fat cells produce estrogen, this disease is often observed in obese women. A similar effect is observed in PCOS.
4. Prostate cancer: Dihydrotestosten (DHT), a stronger version of testosterone and testosterone associated with prostate cancer in men. Boiled prostate cells may grow in response to the increased amount of these hormones.
Mechanisms that bind hormones with cancer
Hormones affect the risk of cancer in several ways –
1. Cell proliferation: In tissues that are sensitive to hormones, hormones such as testosterone and estrogen stimulate cell division. Mutations caused by increasing cell division increase the risk of cancer.
2. DNA damage: A number of hormones have the ability to create metabolites that cause DNA damage and oxidative stress, which can help in cancer development.
3. Activation of receptors: When hormones are attached to certain cell receptors, they initiate processes that can lead to unverified cell division.
4. Suppression of immunity: Unbalanced hormones can impede the immune system to detect and eliminate aberrant cells, which contributes to the growth of malignant cells.
Risk factors
Dr. Varini N said: “Age, family history, lifestyle choice and medical history – some of the factors that can aggravate hormonal connection with reproductive cancer. From their cumulative hormones, the elderly are more likely to develop hormonal malignancies. The consequences The effects of hormones can be enhanced by genetic inclinations such as mutations in BRCA1 or BRCA2. “
It added: “Vulnerability increases diseases such as PCOS, endometriosis and long -term hormone therapy. Estrogen and progesterone, two female sex hormones, dosed in the fight against fertility. , they slightly increase the risk of cervix and breast cancer. “
Prevention and early detection
Increasing awareness and learning people about early signs and symptoms are the most popular and successful preventive strategy. Varini’s d -rin concluded: “Hormone levels can be adjusted by using a balanced diet, often training and maintaining healthy weight. For early detection, conventional checks such as PSA tests, pelvic and mammograms are crucial. Preventive interventions such as Selective estrogen receptor modulators (SERMS) or preventive surgery can be examined for high -risk patients.
Refusal: This article is intended only for information purposes rather than to replace professional medical advice. Always seek the advice of a doctor with any medical issues.
